Anticoagulants: dose control methods and inhibitors

These days, anticoagulants are in great demand. They used as a prophylaxis for thromboembolic complications various diseases and conditions general therapeutic practice, cardiology, neurology, well obstetrics to manage high-risk pregnancies. The relevance of competent use has come the fore connection with emergence new disease – COVID-19 its serious such developing thrombotic storm, which timely applied anticoagulant therapy is key success therapy. risk bleeding should be considered when using any anticoagulant. Age, impaired renal function concomitant antiplatelet agents common factors bleeding. Moreover, only vitamin K antagonists heparin have specific antidotes protamine, respectively. Inhibitors other universal presented inactivated or activated prothrombin complex concentrate recombinant factor VIIa. Hemodialysis effectively reduces dabigatran concentration, charcoal effective case recent oral administration lipophilic drugs. Research on currently available under way, similar testing types that sufficiently preventing treating minimal hemorrhagic. main contraindication doctor's ignorance mechanisms drug action opportunities suppressing effect.